Middle-Aged Man With Rash

A middle-aged man with newly diagnosed HIV infection and rash.

TEN is a rare cutaneous drug reaction associated with high morbidity and mortality. The underlying pathogenic mechanisms are poorly understood. Development of an effective treatment algorithm has been hampered by the low incidence of this disorder, incomplete knowledge of the mechanisms of epidermal death, and lack of large controlled trials to evaluate therapeutic interventions.

Chronic rash in a middle-aged woman.

Volume 85, Number 10 www.aafp.org/afp American Family Physician 987 A 53-year-old woman presented with a pruritic rash on the back of her left thigh that had persisted for six months. She had no new contacts and had not taken any new medications. The rash had partially responded to a moderate-potency topical steroid cream, but never fully resolved. She had a history of uncontrolled type 2 diabe...

Middle aged man with groin pain.

McArdle syndrome with recurrent rhabdomyolysis in a middle aged man.

A 44-year old male estate labourer presented with severe muscle pains and passing dark urine of two days duration. Six hours prior to the onset of symptoms, he sustained a fall from height of about six feet. The muscle pains progressively worsened over the next two days and he was almost immobilised due to severe generalised muscle pain by the second day of the illness. On the same day, he noti...

A middle-aged man with scrotal and perineal pain.

A 53-year-old man, with a history of metastatic lung cancer treated with chemotherapy, presented with a high fever and in poor general condition in September 2008. He was found after slipping and falling in a toilet and was therefore admitted to hospital. He appeared to be suffering acute sepsis and a physical examination revealed tenderness over his scrotum and perianal region. An X-ray of his...